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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
AffinityImmuno/Anti PEG antibody ELISA (human IgG specific) Catalog EL-141-PEG-hIGG/Coated microtiter plate, 96 wells,QC samples - 6x250ul,10X assay/wash buffer - 50ml,500X biotinylated PEG(5KDa) - 50ul,1000X detection reagent - 17ul,TMB - 12ml,TMB st
产品编号:EL-141-PEG-hIGG
市  场 价:¥12799.80
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>多肽合成>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$639.99
品      牌: AffinityImmuno
公      司:AffinityImmuno
公司分类:
AffinityImmuno/Anti PEG antibody ELISA (human IgG specific) Catalog EL-141-PEG-hIGG/Coated microtiter plate, 96 wells,QC samples - 6x250ul,10X assay/wash buffer - 50ml,500X biotinylated PEG(5KDa) - 50ul,1000X detection reagent - 17ul,TMB - 12ml,TMB st
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Description

INTRODUCTION
Polyethylene glycol (PEG) chains are often used to modify therapeutic biologic agents in order to prolong the circulating half-life of the modified protein by slowing proteolytic degradation. It has been reported that repeat injections of PEGylated proteins can induce anti-PEG antibodies. Anti-PEG antibodies can result in rapid clearance and decreased drug efficacy (accelerated blood clearance, or ABC, phenomenon).
PRINCIPLE OF THE ASSAY
This immunogenicity assay measures the presence of human IgG in serum or plasma that bind to immobilized PEG using the direct ELISA technique. The supplied stretavidin precoated 96 well microplate is incubated with biotinylated PEG (5KDa). After washing, quality control and test samples are pipetted into the appropriate wells. Anti-PEG antibodies bind the immobilized PEG. After washing, detection antibody (anti human IgG Peroxidase) is added. Any unbound antibody enzyme reagent is removed with a final wash and a substrate solution is added to the wells for color development. Color development is proportional to the amount of anti-PEG IgG.

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AffinityImmuno2019年4月 - 新的Pembrolizumab(Keytruda)药代动力学ELISA现已上市我们很高兴地宣布我们的Pembrolizumab(Keytruda®)药代动力学ELISA试剂盒的发布Pembrolizumab ELISA试剂盒旨在测量整个 免疫Pembrolizumab在生物基质中具有高特异性和敏感性。

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